Graft Versus Host Disease is a consequence of donor immune cells attacking the recipient, following a stem cell or bone marrow transplant. Approximately 60% of GVHD patients have ocular involvement resulting in severe dry eye. Patients who have ocular GVHD have debilitating dryness that is stubborn to aggressive therapy. Bandage contact lenses offer temporary protection for the compromised ocular surface. Scleral lenses are often utilized for managing ocular GVHD. The fluid reservoir that scleral lenses hold helps to continuously bathe the anterior ocular surface, acting like as a more permanent liquid band aid. A 2008 paper by Schornack et al. reported on a retrospective case series of five patients (10 eyes) who had ocular GVHD and experienced subjective improvements in comfort with scleral lenses after conventional therapy had failed.