Scleral lenses hold a liquid reservoir and ideally should be without air bubbles when properly fit and applied.  If excessive saline is spilled from the lens during application or the lens is first positioned off center, then air bubbles may be present.  Small to medium bubbles will not affect vision, fit, or comfort.  However, if the lens does not feel comfortable and/or the vision is disrupted, then the lens will have to be reapplied.  The photograph shows an air bubble secondary to application error that is not affecting vision or comfort.